Players can learn a great deal about which cards are still available and modify their strategy by keeping a close eye on the cards that opponents have picked up & discarded. A player may cotummy eastnclude that there are no more 6s in play if, for instance, they observe that all four 6s have been played and modify their strategy accordingly. Handling Joker Cards. Keeping an eye on your Joker cards is another clever strategy to win the game. Jokers are very useful for finishing combinations because they can be used as wildcards, replacing any other card in a set or run.